Cystine/glutamate transporter - Wikipedia
The SLC7A11 gene encodes a sodium-independent cystine - glutamate antiporter that is chloride dependent, also known as xCT. Along with a heavy chain subunit from SLC3A2, the SLC7A11 light …
SLC7A11 Gene - GeneCards | XCT Protein | XCT Antibody
Nov 14, 2025 · In this system, designated Xc (-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma …
xCT: A Critical Molecule That Links Cancer Metabolism to Redox ...
Nov 4, 2020 · In recent years, the xCT molecule has been found to play an important role in tumor growth, progression, metastasis, and multidrug resistance in various types of cancer. Interestingly, …
xCT (SLC7A11)-mediated metabolic reprogramming promotes non …
May 23, 2018 · Recent studies demonstrated that smoking could induce the expression of xCT (SLC7A11) in oral cancer cells, suggesting that overexpression of xCT may support lung tumor …
xCT: A Critical Molecule That Links Cancer Metabolism to Redox ...
Nov 4, 2020 · In recent years, the xCT molecule has been found to play an important role in tumor growth, progression, metastasis, and multidrug resistance in various types of cancer. Interestingly, …
SLC7A11/xCT-mediated Cystine Uptake Regulates Intracellular …
Background/Aim: In a tongue–submandibular lymph node (SLN) metastasis model, the cystine/glutamate transporter solute carrier family 7, member 11 (Slc7a11), also known as xCT, was …
A xCT role in tumour-associated ferroptosis shed light on novel ...
Oct 25, 2022 · Solute carrier family 7 member 11 (SLC7A11; also known as xCT), a key component of the cystine/glutamate antiporter, is essential for the maintenance of cellular redox status and the …
Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient ...
The cystine/glutamate antiporter SLC7A11 (also commonly known as xCT) functions to import cystine for glutathione biosynthesis and antioxidant defense and is overexpressed in multiple human cancers.
SLC7A11 expression level dictates differential responses to oxidative ...
Jun 21, 2023 · The cystine transporter solute carrier family 7 member 11 (SLC7A11; also called xCT) protects cancer cells from oxidative stress and is overexpressed in many cancers.
Honoring a Geosciences Pioneer: Professor Peter Heaney's Retirement …
Jul 18, 2025 · Further advancements in geosciences research are evident in the application of techniques like X-ray Computed Tomography (XCT). In ore geology, the integration of multi-scale …