A combination of two mutated copies of the FECH gene in each cell, or one mutated copy of the gene and one low-expression allele, is necessary for erythropoietic protoporphyria to develop.

Although these questions remain, this article sheds light on FECH, which has not received much attention, and clari fied the point of action of vemur-afenib, which frequently causes renal injury.

Jun 2, 2020 · Here, we investigated the inhibition of FECH using genetic and chemical approaches in the oxygen-induced retinopathy (OIR) mouse model. In OIR mice, FECH expression is upregulated …

A Novel Mutation in the FECH Gene in a Czech Family with Erythropoietic Protoporphyria and a Population Study of IVS3-48C Variant Contributing to the Disease (hepatoerythropoietic porphyria / …

Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 14466-1-AP (FECH Antibody) at dilution of 1:200 (under 40x lens).

Activity of the heme synthesis enzyme ferrochelatase (FECH) is implicated in multiple diseases. In particular, it is a mediator of neovascularization in the eye and thus an appealing therapeutic target …